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ZENODO
Doctoral thesis . 2023
License: CC BY
Data sources: ZENODO
ZENODO
Thesis . 2023
License: CC BY
Data sources: Datacite
ZENODO
Thesis . 2023
License: CC BY
Data sources: Datacite
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FORMULATION AND EVALUATION OF ITOPRIDE HYDROCHLORIDE CONTROLLED RELEASE TABLETS

descriptionPublicationkeyboard_double_arrow_right Thesis , Doctoral thesis 27 Oct 2023Publisher:Zenodo
Authors: Sirigadha Ramprasad;

doi: 10.5281/zenodo.10047809 , 10.5281/zenodo.10047808

FORMULATION AND EVALUATION OF ITOPRIDE HYDROCHLORIDE CONTROLLED RELEASE TABLETS

Abstract

The aim of the present study was to develop controlled release formulation of Itopride hydrochloride to maintain constant therapeutic levels of the drug for over 12 hrs. HPMC K 15M, HEC 2M, HPC 2M were employed as polymers. All the formulations were passed various physicochemical evaluation parameters and they were found to be within limits. From the dissolution studies it was evident that the formulation (F7) showed better and desired drug release pattern i.e., 98.68 % in 12 hours. It contains the HPC 2M polymer. It followed Zero order release kinetics mechanism. Keywords: Itopride hydrochloride, HPMC K 15M, HEC 2M, HPC 2M and Controlled release tablets.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average