This report analyses the openness of publications from research funded by NWO and ZonMW in 2022. The research was based exclusively on openly accessible metadata. Overall, 93% of the articles that were detected have been made available open access using one of the available open access routes (NWO: 93,1%; ZonMw: 92,7%). This is an increase compared to 2021 (90%) and 2020 (85%). At least 64% of the included NWO and ZonMw publications of 2022 (3.688 out of 5.763) has been published via Gold, Hybrid, under a transformative agreement, or Green OA, with a CC-BY license and is therefore fully Plan S compliant. Being Plan S compliant is mandatory for NWO and ZonMw research granted from 2021 onwards; many of the current publications analysed, are likely from grants from before 2021. It is recommended that the future strategy of NWO and ZonMw should focus not just on reaching the 100% open access, but also on the costs, monitoring, development and quality aspects of open access in general.