Introduction. The relevance of studying the factors influencing employee satisfaction in a medical organization is driven by the necessity to improve motivation, work quality, and patient care levels, as well as to reduce staff turnover and ensure stability in the healthcare sector. The aim of the study was to investigate the effects of compensation management on workers satisfaction in Nkwen Baptist Hospital Bamenda. The area of study was Nkwen Baptist Health Centre of the North West Region of Cameroon. Methodology. The study adopted causal research design. The study made use of survey data collected with the help of a structured questionnaire through random sampling and analysed using both descriptive and inferential statistics. Results. Results from the ordinary least square revealed that direct financial compensation, indirect financial compensation, and non-financial compensation has a positive impact on workers’ satisfaction.Recommendation. It was recommended that the management of Nkwen Baptist Hospital should ensure that the direct financial compensation provided to workers is competitive within the health care industry; evaluate the company’s benefits package to ensure it is comprehensive and meets the needs of the workforce; gather feedback from employees to understand their preferences and tailor the non-financial compensation offerings accordingly. Conclusion. The findings suggest that fair and competitive compensation packages, transparency, and performance-based incentives are essential for enhancing employee motivation-and job satisfaction, reduce turnover rates, and attract top talent. Novelty. The findings contribute to the existing body of knowledge on compensation management and employee satisfaction in the healthcare sector, Nkwen Baptist Hospital in Cameroon, a context that has received limited attention in previous research.