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Survival of the fittest or best adapted: HLA-dependent tumor development

descriptionPublicationkeyboard_double_arrow_right Article 27 May 2010 Italy Publisher:PAGEPress PublicationsJournal:Journal of Nucleic Acids Investigation, volume 1, page 9 (issn: 2035-6005, eissn: 2036-7996, Copyright policy )
Authors: Masucci GV; Andersson E; Villabona L; Helgadottir H; Bergfeldt K; CAVALLO, Federica; FORNI, Guido; +4 Authors

doi: 10.4081/jnai.2010.1654 , 10.4081/jnai.1654 , 10.4081/jnai.2010.e9

handle: 2318/124336

Survival of the fittest or best adapted: HLA-dependent tumor development

Abstract

The major histocompatibility complex (MHC) comprises a set of genes that are critical to immunity and surveillance against neoplastic transformation. There is increasing evidence that the MHC antigens not only regulate antitumor immune responses in experimental animal models but directly correlate with survival and prognosis of patients with diverse types of cancers. MHC antigens may in the future function as potential biomarkers for prognosis and allow selection of cancer patients for intensive therapy.

Country
Italy
Related Organizations
Keywords

Biochemistry

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 3
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
3
Average
Average
Average
Green
gold
Related to Research communities
Knowmad Institut
Cancer Research