The biological process of Wound healing comprises the trauma and pathologic condition of the oral mucosa.For this requires proper management so the wound heal faster and without any complication.The strong indicator of wound healing is the increase in number of fibroblast cells in the oral mucosa. The remodelling phase of wound healing shows decreasing fibroblast cell proliferation and then collagen fibres are synthesized. Noni plant have tremendous medicinal uses, by observing this fact Noni leaf (Morinda citrifolia L.), a part of the noni plant, was successfully used in present research to make ointments to heal soft tissue in wounds. The leaves of Morinda have potential chemical compounds such as glycosides, sterol, amino acids and scopletin that may be useful in the wound repair process. In addition to this Morinda citrifolia leaf contains active substances such as saponin, tannin, polyphenol flavonoid, and triterpen. The purpose of this research is to discover the activeness of the Morinda citrifolia leaves extracts in normal solvent such as ethanol to make ointments in order to arrest the growth of the bacteria.[1] By using macernation extract of morinda leaves done successfully, ointment made and done the evalution test such as spreadibilty, diffusion study, washability and very important antimicrobial test. The entire test gives corresponding good result, so the present research showing good response to healing mechanism of wounds.