This study aims to evaluate the potential of ERA5 precipitation and temperature reanalysis for snow water equivalent (SWE) simulation by considering the role of catchment spatial scale in controlling the errors obtained by comparison with corresponding SWE simulations from ground stations. This is obtained by exploiting a semi-distributed snowpack model (TOPMELT) implemented over the upper Adige River basin in the Eastern Italian Alps, where 16 sub-catchments of varying sizes are considered. The comparison is carried out from 1992 to 2019. The findings show that ERA5 precipitation overestimated low-intensity rainfall (drizzle problem) and underestimated high-intensity rainfall, while ERA5 temperature underestimated observations. The overestimation of low-intensity rainfall created fictitious low-intensity snowfall events, which, when combined with colder ERA5 temperature, resulted in delayed snowmelt and increased fictitious snow-cover days over the study area. The quantile mapping (QM) technique was used to remove errors in ERA5 variables. It was shown that ERA5 could struggle to resolve the orographic enhancement in precipitation, which may be particularly important during high-SWE years. This reduces the positive precipitation bias during those years, thus reducing comparatively the ability of the quantile mapping technique to correct for bias homogeneously during all years. This study highlighted the importance of temperature correction over precipitation correction in SWE simulation, particularly for smaller basins.