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Method Devlopment of Apremilast API in Methanol by UV-Visible Spectroscopy

Authors: Deepak Chandra Sharma; G. Rajan; Pranshu Tangri | Preeti Kothiyal;

Method Devlopment of Apremilast API in Methanol by UV-Visible Spectroscopy

Abstract

A simple, precise, accurate, cost effective stability indicating UV Spectrophotometric method has been developed for the estimation of Apremilast. Apremilast shows highest max at 340 nm. Beers law linearity response was found over a concentration range of 10 60 µg mL with good correlation coefficient r2 = 0.9994 . The Proposed spectrophotometric method was validated as per the ICH Q1A R2 guidelines. Hence this method can be safely be employed for the routine quality control analysis of Apremilast. Deepak Chandra Sharma | G. Rajan | Pranshu Tangri | Preeti Kothiyal "Method Devlopment of Apremilast (API) in Methanol by UV-Visible Spectroscopy" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-3 , April 2018, URL: https://www.ijtsrd.com/papers/ijtsrd9675.pdf

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Keywords

Method Development, Apremilast, uv-visible spectroscopy, Analytical chemistry

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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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