The level of globalization of several ASEAN countries has increased for decades. This increasing level of globalization shows that these countries are increasingly open in terms of economic, social and political aspects. It is widely debated the impact of this openness on developing countries. This paper aims to see the impact of economic, social and political openness on unemployment in several ASEAN countries. This study uses panel data from six countries in ASEAN from 2010-2015 with the KOF index. The study found that the increase of economic and social globalization has an impact on reducing unemployment in ASEAN, while the increase of political globalization could increase unemployment in ASEAN.