Introduction: Anthropometric measurements of Neonatal serve as a vital clinical tool for identifying small or large newborns.These measurements also playa crucial role in assessing the potentialoutcomes of newborns,helping to predict future risksof morbidity or mortality. The purpose of this study was to determine the average anthropometric measurements representative of Khartoum State, Sudan’s newborn population and to examine the relationship between these measurements and maternal factors. Methodology: This study employed a descriptive observational design acrossthree hospitals located in Khartoum: Omdurman Maternity Hospital, Bahri Teaching Hospital, and Saad Abo Aila Hospital. The study included 794 mothers and their newbornsafter meetingthe inclusion and exclusion criteria within the first 72 hours postdelivery. Neonatal measurements, including birth weight, crownheel length, and head and chest circumference, were taken for those who met the criteria.Statistical Package for Social Science (SPSS) version 20 to present means and generate tables and figures. Chi-square test used to assess the significant of relationship between different maternal and neonatal variables. All ethical considerations were maintained.