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International Journal of Advanced Research
Article . 2025 . Peer-reviewed
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MANAGEMENT OF LOW BLOOD PRESSURE DURING SPINAL ANAESTHESIA FOR CAESAREAN SECTION: COMPARISON BETWEEN EPHEDRINE AND LOW-DILUTE NOREPINEPHRINE

Authors: Chiguer Chaimae; Raja Amine; Fattah Ayoub; Afif Amine; El Harit Marouane; El Yousoufi Smael; Salmi Said;

MANAGEMENT OF LOW BLOOD PRESSURE DURING SPINAL ANAESTHESIA FOR CAESAREAN SECTION: COMPARISON BETWEEN EPHEDRINE AND LOW-DILUTE NOREPINEPHRINE

Abstract

This prospective study, conducted over six months at the Ibn Rochd University Hospital in Casablanca, compared the efficacy of weakly diluted norepinephrine and ephedrine for the management of hypotension induced by spinal anesthesia during caesarean sections. Among 120 patients (mean age: 25.5 5.5 years), norepinephrine was distinguished by improved hemodynamic stability, ensuring more precise heart rate control (maximum of 97.47 bpm vs. 133.7 bpm) and higher systolic blood pressure (126.19 mmHg vs. 80.84 mmHg), while optimally preserving the pH of umbilical cord blood (7.25 versus 7.21). Despite comparable gasometric parameters and Apgar scores between groups, a dose of 16 mcg norepinephrine demonstrated slightly better hemodynamic control than that of 8 mcg. These results suggest that weakly diluted norepinephrine represents a safer and more effective therapeutic alternative to ephedrine in this clinical setting, thus ensuring better maternal and fetal safety.

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold