
handle: 10651/80707
Complete description of the obtention of new aptamers against the antibiotic Vancomycin by using Magnetic-bead SELEX, their characterization by SPR, generation of the tridimensional structure for molecular docking and the development of adisposable electrochemical aptasensor for cost-effective and rapid monitoring of Vancomycin in serum. Validation with clinical samples from hospitalized patient under antibiotic treatment and comparsion with results obtained in the clinical laboratory.
APTAMD software, electrochemical aptasensor, vancomycin, aptamer, Magnetic-bead SELEX, molecular docking, clinical serum monitoring
APTAMD software, electrochemical aptasensor, vancomycin, aptamer, Magnetic-bead SELEX, molecular docking, clinical serum monitoring
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