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Open Schools Journal for Open Science
Article . 2020 . Peer-reviewed
License: CC BY NC SA
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Open Schools Journal for Open Science
Article
License: CC BY NC SA
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Other literature type . 2020
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Drug targeting in cancer therapy

Authors: L. Nys; P. Raeuschl; I.A. Joubert; M. Geppert; S. Ess; M. Himly; R. Nestelbacher;

Drug targeting in cancer therapy

Abstract

Drug targeting enables the local reslease of medication at the desired site or organ. This ensures that the drug asserts its effects focused to a small site, minimising systematic side effects. Drug targeting has been successfully applied in cancer therapy and can be performed actively or passively. During passive drug targeting, carriers containing the active cancer drug concentrate within the tumour tissue due to increased blood circulation and vascular permeation (enhanced penetration retention principle). Active drug targeting on the other hand, facilitates ligand-recepto interacions.

Country
Australia
Keywords

thermodox, liposomes, radio frequency ablation, nano capsules, chemotherapy, doxorubicin

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
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Cancer Research