Fagopyrum tibeticum is a small woody shrub, which was initially classified under the genus Parapteropyrum (Polygonaceae) as Parapteryrum tibeticum. However, recent molecular evidences has shown that it should belong to Fagopyrum. By integrating cytological, morphological, and molecular biology evidences, we compare F. tibetium with the other Fagopyrum species, once again proving that F. tibeticum should belong to the Fagopyrum genus. Moreover, F. tibeticum is the only existing hexaploid species in the genus Fagopyrum. The speciation of F. tibeticum may be related to the uplift of the Qinghai Tibet Plateau and the distinctive climate environment.