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Cloning and regional assignment of the human myosin heavy chain 12 (MYH12) gene to chromosome band 15q21

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1995 English Publisher:S. Karger AGJournal:Cytogenetic and Genome Research, volume 69, pages 53-58 (issn: 1424-8581, eissn: 1424-859X,

Authors: Moore, K. J.; Testa, J. R.; Francke, U.; Milatovich, A.; Copeland, N. G.; Jenkins, N. A.;

doi: 10.1159/000133937

pmid: 7835087

Cloning and regional assignment of the human myosin heavy chain 12 (MYH12) gene to chromosome band 15q21

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Abstract

Sequences encoding 1,235 bp of the human myosin heavy chain 12 (MYH12) gene have been cloned from a human brain cDNA library by PCR amplification. The human sequence is 95.8% identical to the mouse sequence at the amino acid level, indicating that the MYH12 gene has been evolutionarily well conserved. Somatic cell hybrid analysis and in situ hybridization place the MYH12 gene on human chromosome 15, at band q21, and extend distally the known region of chromosome 15 linkage homology on mouse chromosome 9.

Related Organizations

Fox Chase Cancer Center
United States
Dignity Health
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Stanford Medicine
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Stanford University
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Methodist Hospital
United States

Keywords

Male, Chromosomes, Human, Pair 15, DNA, Complementary, Base Sequence, Genetic Linkage, Brain, Chromosome Mapping, Hominidae, Biological Evolution, Mice, Cerebellum, Child, Preschool, Animals, Humans, Female, Amino Acid Sequence, Cloning, Molecular, Conserved Sequence, Crosses, Genetic, Gene Library

3 Research products, page 1 of 1

Homo sapiens (human) myosin heavy chain 12
2018IsRelatedTo
MYH12=myosin heavy chain 12 [human, brain, mRNA Partial, 1235 nt].
2018IsRelatedTo
Unconventional myosin-Va
2017IsRelatedTo

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