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Recolector de Ciencia Abierta, RECOLECTA
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CRISPR-Cas13a-Based Assay for Accurate Detection of OXA-48 and GES Carbapenemases

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 17 Aug 2023 Spain English Publisher:American Society for MicrobiologyJournal:Microbiology Spectrum, volume 11 (eissn: 2165-0497, Copyright policy )
Authors: Ortiz-Cartagena, Concha; Pablo-Marcos, Daniel; Fernández-García, Laura; Blasco, Lucía; Pacios, Olga; Bleriot, Inés; Siller, María; +10 Authors

doi: 10.1128/spectrum.01329-23

pmid: 37466441

pmc: PMC10434040

handle: 20.500.12105/16305 , 10261/350023

CRISPR-Cas13a-Based Assay for Accurate Detection of OXA-48 and GES Carbapenemases

Abstract

Carbapenems are one of the last-resort antibiotics for defense against multidrug-resistant pathogens. Multiple nucleic acid amplification methods, including multiplex PCR, multiplex loop-mediated isothermal amplification (LAMP) and multiplex RPAs, can achieve rapid, accurate, and simultaneous detection of several resistance genes to carbapenems in a single reaction.

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Keywords

CRISPR-Cas13a, detection, GES, OXA-48, LAMP, CRISPR-Cas13a, detection, GES, Microbiology, QR1-502, beta-Lactamases, Detection, Bacterial Proteins, Carbapenems, LAMP, Nucleic Acids, Humans, Multiplex Polymerase Chain Reaction, OXA-48, Research Article

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
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16
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87
51
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