Downloads provided by UsageCountsMajor Susceptibility Locus for Prostate Cancer on Chromosome 1 Suggested by a Genome-Wide Search
Copyright policy ) J R, Smith; D, Freije; J D, Carpten; H, Grönberg; J, Xu; S D, Isaacs; M J, Brownstein; G S, Bova; H, Guo; P, Bujnovszky; D R, Nusskern; J E, Damber; A, Bergh; M, Emanuelsson; O P, Kallioniemi; J, Walker-Daniels; J E, Bailey-Wilson; T H, Beaty; D A, Meyers; P C, Walsh; F S, Collins; J M, Trent; W B, Isaacs;
Major Susceptibility Locus for Prostate Cancer on Chromosome 1 Suggested by a Genome-Wide Search
Despite its high prevalence, very little is known regarding genetic predisposition to prostate cancer. A genome-wide scan performed in 66 high-risk prostate cancer families has provided evidence of linkage to the long arm of chromosome 1 (1q24-25). Analysis of an additional set of 25 North American and Swedish families with markers in this region resulted in significant evidence of linkage in the combined set of 91 families. The data provide strong evidence of a major prostate cancer susceptibility locus on chromosome 1.
- National Institutes of Health United States
- Johns Hopkins University School of Medicine United States
- University of Michigan–Ann Arbor United States
- Johns Hopkins Medicine United States
- University of Michigan–Flint United States
Adult, Aged, 80 and over, Genetic Markers, Male, Likelihood Functions, Genetic Linkage, Chromosome Mapping, Prostatic Neoplasms, Oncogenes, Middle Aged, Statistics, Nonparametric, Pedigree, Genes, Chromosomes, Human, Pair 1, Risk Factors, North America, Humans, Genetic Predisposition to Disease, Dinucleotide Repeats, Aged
Adult, Aged, 80 and over, Genetic Markers, Male, Likelihood Functions, Genetic Linkage, Chromosome Mapping, Prostatic Neoplasms, Oncogenes, Middle Aged, Statistics, Nonparametric, Pedigree, Genes, Chromosomes, Human, Pair 1, Risk Factors, North America, Humans, Genetic Predisposition to Disease, Dinucleotide Repeats, Aged
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).721 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 0.1% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 0.1% views 65 downloads 48 - 65views48downloads
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These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Influence provided by BIP!impulseImpulse provided by BIP!
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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