Bats Are Natural Reservoirs of SARS-Like Coronaviruses

descriptionPublicationkeyboard_double_arrow_right Article 28 Oct 2005 Australia, United States, Australia English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science, volume 310, pages 676-679 (issn: 0036-8075, eissn: 1095-9203,

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Authors: Li, Wendong; Shi, Zhengli; Yu, Meng; Ren, Wuze; Smith, Craig; Epstein, Jonathan H.; Wang, Hanzhong; +10 Authors

Bats Are Natural Reservoirs of SARS-Like Coronaviruses

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Abstract

Severe acute respiratory syndrome (SARS) emerged in 2002 to 2003 in southern China. The origin of its etiological agent, the SARS coronavirus (SARS-CoV), remains elusive. Here we report that species of bats are a natural host of coronaviruses closely related to those responsible for the SARS outbreak. These viruses, termed SARS-like coronaviruses (SL-CoVs), display greater genetic variation than SARS-CoV isolated from humans or from civets. The human and civet isolates of SARS-CoV nestle phylogenetically within the spectrum of SL-CoVs, indicating that the virus responsible for the SARS outbreak was a member of this coronavirus group.

Countries

Australia, United States, Australia

Related Organizations

State Key Laboratory of Virology
China (People's Republic of)
Queensland Department of Agriculture and Fisheries
Australia
Chinese Academy of Sciences
China (People's Republic of)
Department of Agriculture and Fisheries
Australia
Wuhan Institute of Virology
China (People's Republic of)

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Keywords

Sars, Coronaviruses, SARS (Disease), bat, Severe Acute Respiratory Syndrome, Communicable Diseases, Emerging, Polymerase Chain Reaction, Disease Outbreaks, Chiroptera, Bats, Chlorocebus aethiops, Viridae, Chordata, Phylogeny, biotic associations, corona viruses, covid, Biodiversity, SARS Virus, covid-19, Severe acute respiratory syndrome-related coronavirus, Mammalia, CETAF-taskforce, 570, China, Asia, Coronaviridae, Molecular Sequence Data, bats, 610, Genome, Viral, virus-host, Viverridae, pathogen-host, Virology, Animals, Humans, Animalia, biotic relations, Amino Acid Sequence, Vero Cells, Henipavirus, Disease Reservoirs, Genetic Variation, pathogens, Sequence Analysis, DNA, Veterinary epidemiology. Epizootiology, biotic interaction, Coronavirus, Mutation

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