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S-adenosyl-l-homocysteine hydrolase links methionine metabolism to the circadian clock and chromatin remodeling

descriptionPublicationkeyboard_double_arrow_right Article 18 Dec 2020 United Kingdom, France, United Kingdom, United States English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science Advances, volume 6 (eissn: 2375-2548, Copyright policy )Funded by:NIH | Rewiring the Circadian Cl..., EC | MetEpiClock, NIH | Systems Biology of Morpho... +7 projects
Authors: Greco, Carolina Magdalen; Cervantes, Marlene; Fustin, Jean-Michel; Ito, Kakeru; Ceglia, Nicholas; Samad, Muntaha; Shi, Jiejun; +12 Authors

doi: 10.1126/sciadv.abc5629

pmid: 33328229

pmc: PMC7744083

S-adenosyl-l-homocysteine hydrolase links methionine metabolism to the circadian clock and chromatin remodeling

Abstract

The S-adenosylhomocysteine (SAH) hydrolyzing enzyme AHCY functionally links the circadian clock to methionine metabolism.

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Keywords

[SDV]Life Sciences [q-bio], 1.1 Normal biological development and functioning, 590, 610, CLOCK Proteins, Mice, Methionine, Circadian Clocks, Genetics, Animals, Research Articles, Biomedical and Clinical Sciences, Adenosylhomocysteinase, Human Genome, Neurosciences, ARNTL Transcription Factors, 600, Biological Sciences, Chromatin Assembly and Disassembly, S-Adenosylhomocysteine, Chromatin, Circadian Rhythm, [SDV] Life Sciences [q-bio], Biochemistry and Cell Biology, Generic health relevance, Sleep Research

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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