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Conference object . 2025
License: CC BY
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https://doi.org/10.1117/12.304...
Article . 2025 . Peer-reviewed
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Large-area dynamic contrast MHz optical coherence tomography for label-free imaging of porcine tissue

descriptionPublicationkeyboard_double_arrow_right Article , Conference object 19 Mar 2025Publisher:SPIEJournal:Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIX
Authors: Burhan, Sazgar; Göb, Madita; Pieper, Mario; Laedtke, Tjalfe; Grahl, Thorge; Münter, Michael; Schulz-Hildebrandt, Hinnerk; +3 Authors

doi: 10.1117/12.3046216

Large-area dynamic contrast MHz optical coherence tomography for label-free imaging of porcine tissue

Abstract

We demonstrate a 3.2 MHz-OCT system for inter-volumetric dynamic optical coherence tomography of ex vivo porcine kidney tissue. Employing a home-built Fourier Domain mode locking (FDML) laser with a 1310 nm wavelength, the system achieved a lateral resolution of 3.48 μm and a frame rate of 612 Hz. A motorized XYZ positioning stage enabled the precise acquisition of multiple volumes, which were seamlessly stitched together to generate a comprehensive dataset with a total area of 2.6 × 2.6 mm2. Validations against histological sections confirmed the system’s ability to visualize cellular tissue structures.

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    selected citations
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 3
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
3
Top 10%
Average
Average