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Clinical Transplantation
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Clinical Transplantation
Article . 2019 . Peer-reviewed
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A review of the use of transient elastography in the assessment of fibrosis and steatosis in the post–liver transplant patient

Authors: Adam C. Winters; Rasham Mittal; Thomas D. Schiano;

A review of the use of transient elastography in the assessment of fibrosis and steatosis in the post–liver transplant patient

Abstract

AbstractLiver biopsy is considered the gold standard method for diagnosing and staging liver disease, particularly in the post‐liver transplant setting. Given the invasive nature of biopsy, alternate means for accurately assessing liver fibrosis and steatosis are preferred especially as the number of patients with fatty liver disease is increasing. Transient elastography has been validated as a useful tool for evaluation of liver fibrosis, as has controlled attenuation parameter index as a tool for assessing steatosis. It is a non‐invasive, rapid, and highly reproducible approach to demonstrate the presence of fibrosis among non‐transplant patients with chronic liver disease of various etiologies. However, it has not yet found wide acceptance in liver transplant recipients. There are few published studies evaluating the merits and applicability of transient elastography to assess allografts after liver transplantation. We review the published data on the use of transient elastography with concurrent controlled attenuation parameter in liver transplant recipients and recommend its greater use to follow allograft function over time.

Keywords

Liver Cirrhosis, Non-alcoholic Fatty Liver Disease, Elasticity Imaging Techniques, Humans, Prognosis, Liver Transplantation

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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