The 5G New Radio (NR) access technology defines multiple numerologies to support a wide range of carrier frequencies, deployment scenarios, and variety of use cases. In this paper, we consider a resource allocation problem to efficiently support multiple numerologies simultaneously. We assume frequency division multiplexing (FDM) of numerologies in a time division duplex (TDD) system with a self-contained slot format. We focus on optimizing the numerology subband (SB) configuration, as well as the duplexing ratio between downlink (DL) and uplink (UL) directions within each SB. The optimization problem minimizes the weighted sum of the normalized load (NL) for each SB in each direction. We prove that our optimization problem is convex and, furthermore, we derive the optimal closed-form expressions for the numerology SB configuration and the DL-UL duplexing ratio per SB. The effectiveness of the proposed resource allocation is validated through an end-to-end ns-3 based simulator, which shows how the optimization of the NLs is translated into an improved throughput and delay performance.