The LibraEDT software has been developed to enhance and automate 3D electron diffraction (3D-ED) experiments by addressing key challenges such as crystal tracking, low-fluence data acquisition and better data management. This tool significantly improves both the accuracy and efficiency of ED workflows, particularly when applied to beam-sensitive materials. The utility of this approach is demonstrated through the structural analysis of a known beam-sensitive organic crystal, as well as a novel and previously unreported zinc-based metal–organic framework incorporating protocatechuic acid.