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</script>pmid: 19121772
We sought to summarize major recent studies in the field of dietary sodium intake and arterial blood pressure, and discuss the following trials. INTERSALT: Sodium intake correlates with the rise in blood pressure with age, but not with the prevalence of hypertension. The population study identified a minimal impact of sodium intake on blood pressure (0.9 mm Hg/10 mmol difference in salt intake). DASH: This diet induced significant reductions in blood pressure compared with the control diet. Further decreases were observed with DASH and a 50 mmol/day sodium intake. VANGUARD: Blood pressure was inversely related to urinary potassium, calcium and magnesium but not to sodium excretion. TONE: Cardiovascular events were highest in the usual care group (83%) and lowest in the sodium reduction-plus-weight loss group (56%). META-ANALYSIS: A systematic review of 11 long-term controlled randomized trials reported a small decrease (1.1 mm Hg) in median systolic but not diastolic blood pressure with a reduced dietary sodium intake. In conclusion, (1) sodium restriction in hypertensive patients reduces blood pressure, and (2) the long-term impact of reduced salt intake on blood pressure, mortality, and morbidity remains to be defined.
Aging, Systole, Blood Pressure, Diet, Sodium-Restricted, Cardiovascular Diseases, Diastole, Hypertension, Weight Loss, Potassium, Humans, Kidney Failure, Chronic, Calcium, Magnesium, Sodium Chloride, Dietary, Randomized Controlled Trials as Topic
Aging, Systole, Blood Pressure, Diet, Sodium-Restricted, Cardiovascular Diseases, Diastole, Hypertension, Weight Loss, Potassium, Humans, Kidney Failure, Chronic, Calcium, Magnesium, Sodium Chloride, Dietary, Randomized Controlled Trials as Topic
| citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 41 | |
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| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |
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