A novel 18F-labeled clickable substrate for targeted imaging of SNAP-tag expressing cells by PET in vivo

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2021 English Publisher:Royal Society of Chemistry (RSC)Journal:Chemical Communications, volume 57, pages 9,850-9,853 (issn: 1359-7345, eissn: 1364-548X,

Copyright policy )Funded by:DFG | unidentified, EC | Immune-Image

Authors: Depke, Dominic Alexej; Konken, Christian Paul; Rösner, Lukas; Hermann, Sven; Schäfers, Michael; Rentmeister, Andrea;

doi: 10.1039/d1cc03871k

pmid: 34490435

A novel 18F-labeled clickable substrate for targeted imaging of SNAP-tag expressing cells by PET in vivo

- Summary
- Subjects
- Metrics

Abstract

In this work, high-contrast PET imaging of subcutaneous SNAP-tag expressing tumor xenografts is achieved by bioorthogonal covalent targeting with a novel 18F-based radioligand in vivo.

Related Organizations

Keywords

Fluorine Radioisotopes, Neoplasms, Experimental, Mice, Inbred C57BL, Mice, Positron-Emission Tomography, Animals, Female, Fluorescent Dyes

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	7
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%