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https://dx.doi.org/10.1039/d0l...
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Efficient and gentle delivery of molecules into cells with different elasticity via Progressive Mechanoporation

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2021 United Kingdom English Publisher:Royal Society of Chemistry (RSC)Journal:Lab on a Chip, volume 21, pages 2,437-2,452 (issn: 1473-0197, eissn: 1473-0189, Copyright policy )Funded by:EC | REDOXCYCLE, EC | GENSURGE, EC | FLAMIN-GO +2 projects
Authors: Uvizi, Alena; Goswami, Ruchi; Gandhi, Shanil Durgeshkumar; Augsburg, Martina; Buchholz, Frank; Guck, Jochen; Mansfeld, Jörg; +1 Authors

doi: 10.1039/d0lc01224f , 10.5281/zenodo.6577811 , 10.5281/zenodo.6578354 , 10.5281/zenodo.6577810 , 10.5281/zenodo.6578353

pmid: 33977944

pmc: PMC8204113

handle: 21.11116/0000-000A-07FB-4 , 21.11116/0000-000A-07FD-2

Efficient and gentle delivery of molecules into cells with different elasticity via Progressive Mechanoporation

Abstract

Progressive Mechanoporation, a novel mechanoporation method that improves the delivery efficiency of molecules into cells of different elasticity via a multistage cell deformation controlled by a PDMS-based microfluidic platform.

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Keywords

Cell Membrane Permeability, Cell Membrane, Microfluidics, 610, 612, Cell mechanics, Intracellular delivery, Lab on a chip, Mechanoporation, 540, Stress, Mechanical, Transfection, Elasticity, Chemistry, Gene therapy, Stress, Mechanical

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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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