Exploiting cyclodextrins as artificial chaperones to enhance enzyme protection through supramolecular engineering

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2024 Switzerland, Spain English Publisher:Royal Society of Chemistry (RSC)Journal:Nanoscale, volume 16, pages 5,123-5,129 (issn: 2040-3364, eissn: 2040-3372,

Copyright policy )Funded by:EC | FuturEnzyme

Authors: Foroutan Kalourazi, Ali; Amirabbas Nazemi, Seyed; Unniram Parambi, Ajmal Roshan; Muñoz-Tafalla, Ruben; Vidal, Paula; Shahangian, S. Shirin; Guallar, Víctor; +2 Authors

doi: 10.1039/d3nr06044f , 10.26041/fhnw-11812

pmid: 38349359

handle: 2117/403900 , 10261/374703

Exploiting cyclodextrins as artificial chaperones to enhance enzyme protection through supramolecular engineering

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Abstract

Protecting a surface-immobilised enzyme with an enzyme-thin organosilica layer produced using a protein chaperone building block allows drastic improvement in the enzyme's thermal stability.

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Switzerland, Spain

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Keywords

Ensure sustainable consumption and production patterns, Molecular chaperones, Cyclodextrins, Protein Folding, artificial protein chaperone, Surface-Active Agents, enzyme shielding, Simulació per ordinador, Àrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica::Bioinformàtica, 500 - Naturwissenschaften und Mathematik, Protein engineering, http://metadata.un.org/sdg/12, Supramolecular engineering, Enzyme dynamics, Supramolecularengineering, Molecular Chaperones

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