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Nature
Article
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Article . 1985
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Nature
Article . 1985 . Peer-reviewed
License: Springer TDM
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Nature
Article . 1985
Data sources: Europe PubMed Central
https://dx.doi.org/10.1038/316...
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https://dx.doi.org/10.1038/316...
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Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 1985 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 316, pages 701-705 (issn: 0028-0836, eissn: 1476-4687, Copyright policy )
Authors: Derynck, Rik; Jarrett, Julie A.; Chen, Ellson Y.; Eaton, Dennis H.; Bell, John R.; Assoian, Richard K.; Roberts, Anita B.; +2 Authors

doi: 10.1038/316701a0

pmid: 3861940

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

Abstract

The partial amino-acid sequence of purified human transforming growth factor-beta (TGF-beta) was used to identify a series of cDNA clones encoding the protein. The cDNA sequence indicates that the 112-amino acid monomeric form of the natural TGF-beta homodimer is derived proteolytically from a much longer precursor polypeptide which may be secreted. TGF-beta messenger RNA is synthesized in various normal and transformed cells.

Related Organizations
Keywords

Base Sequence, Neoplasms, Transforming Growth Factors, Humans, Amino Acid Sequence, DNA, RNA, Messenger, Peptides

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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