
Integrated structural biology recently elucidated the architecture of Mediator and its position on RNA polymerase II. Here we summarize these achievements and list open questions on Mediator structure and mechanism.
Transcriptional Activation, Mediator Complex, Transcription, Genetic, Humans, RNA Polymerase II, European Research Council
Transcriptional Activation, Mediator Complex, Transcription, Genetic, Humans, RNA Polymerase II, European Research Council
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