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SnapShot: FMRP mRNA Targets and Diseases

Authors: Pasciuto, E; BAGNI, CLAUDIA;

SnapShot: FMRP mRNA Targets and Diseases

Abstract

FMRP, or fragile X mental retardation protein is an RNA-binding protein. Mutations in the FMRP protein have been associated with neurological disease as have a number of its mRNA-binding targets. This SnapShot presents 40 bona fide FMRP targets for which mRNA binding and protein regulation have been robustly reported in mammals along with the diseases with which they have been associated.

Country
Italy
Keywords

570, Brain Diseases, Fragile X Messenger Ribonucleoprotein 1, Animal, Biochemistry, Genetics and Molecular Biology(all), Mental Disorders, Messenger, Brain Disease, Animals; Brain Diseases; Fragile X Mental Retardation Protein; Humans; Mental Disorders; Neoplasms; RNA, Messenger, Fragile X Mental Retardation Protein, Neoplasms, 616, Mental Disorder, Neoplasm, RNA, Settore BIO/13 - BIOLOGIA APPLICATA, Animals, Humans, RNA, Messenger, Human

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    selected citations
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
59
Top 10%
Top 10%
Top 10%
Green
hybrid