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Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression
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Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression
Article . 1993 . Peer-reviewed
License: Elsevier TDM
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Biochimica et Biophysica Acta
Article . 1993
Data sources: Europe PubMed Central
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Cloning and nucleotide sequence of a novel, male-predominant carboxylesterase in mouse liver

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 1993 English Publisher:Elsevier BVJournal:Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, volume 1,174, pages 72-74 (issn: 0167-4781, Copyright policy )
Authors: Rickie Moore; Kaoru Aida; Masahiko Negishi;

doi: 10.1016/0167-4781(93)90093-s

pmid: 7916639

Cloning and nucleotide sequence of a novel, male-predominant carboxylesterase in mouse liver

Abstract

As a family of serine-dependent enzymes, the carboxylesterases (EC 3.1.1.1) demonstrate a broad substrate specificity. Mouse carboxylesterases comprise at least 20 genetically distinct loci. We cloned a full-length cDNA for a novel mouse carboxylesterase, Es-male which was expressed predominantly in male livers. This carboxylesterase consisted of 554 amino acid residues, and exhibited 43% and 42% similarities to the known mouse esterases Es-22 and pEs-N, respectively. Es-male contained a C-terminal ER-retention signal PEEL, indicating that it may be a microsomal carboxylesterase.

Related Organizations
Keywords

Male, Mice, Inbred BALB C, Base Sequence, Molecular Sequence Data, Mice, Sex Factors, Liver, Mice, Inbred DBA, Animals, Amino Acid Sequence, Cloning, Molecular, Carboxylic Ester Hydrolases

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citations
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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