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Article . 1912
License: CC 0
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Naunyn-Schmiedeberg s Archives of Pharmacology
Article . 1912 . Peer-reviewed
License: Springer TDM
Data sources: Crossref
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In welcher Respirationsphase ist die Lunge am besten durchblutet?

Authors: Cloetta, M.;

In welcher Respirationsphase ist die Lunge am besten durchblutet?

Abstract

Die durch die Respiration bedingten Volumveranderungen der Lunge haben, abgesehen von den im Thorax dabei erzeugten Druckunterschieden einen ausgesprochenen Einflus auf die Blutdurchstromung der Lunge. Auf der Hohe der Inspiration ist die Durchblutung am schlechtesten, viel besser bei der Exspiration, am vollkommensten beim Beginn der Inspiration. Aus der Abschatzung der Druckanderungen an der Pulmonalis, dem rechten Ventrikel und der Karotis sowie des Blutgehaltes der Lungen wahrend der verschiedenen Respirationsphasen ergibt sich, das die Verschlechterung der Zirkulation am Ende der Inspiration quantitativ die kurze, am Beginn der letzteren einsetzende Verbesserung ubertrifft. Der Inspirationsvorgang als Ganzes betrachtet schafft somit fur die Durchblutung der Lunge schlechtere Bedingungen als der Exspirationszustand. Die geschilderte Art der gegeseitigen Beeinflussung von Respiration und Zirkulation hat fur den respiratorischen Gaswechsel keine nachteiligen Folgen; sie kann sogar als durchaus zweckmasig angesehen werden. Diese Auffassung uber die Lungenzirkulation ergibt uns auch eine befriedigende Erklarung fur die pathologischen Funktionsstorungen bei Emphysem und Asthma bronchiale einerseits, sowie andererseits fur die auffallend gunstigen Erfolge bei Tuberkulose, wie sie durch die kunstliche Einschrankung der Inspiration bei Anlegung eines kunstlichen Pneumothorax oder durch die chirurgische Thorakoplastik

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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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