Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Naunyn-Schmiedeberg ...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
ZENODO
Article . 1922
License: CC 0
Data sources: ZENODO
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
versions View all 2 versions
addClaim

Die wirksamen Alkaloide des Mutterkorns

Authors: Dale, H. H.; Spiro, K.;

Die wirksamen Alkaloide des Mutterkorns

Abstract

Die beiden Alkaloide des Mutterkorns Ergotoxin (Barger und Caar) und Ergotamin (Stoll) zeigen bei den verschiedenen zur Untersuchung herangezogenen Tierarten und Organen keine qualitativen Differenzen der Wirkung. Wenn eine solche quantitativer Art besteht, so ist sie nur klein und es bedurfte zu ihrem Nachweis noch einer viel groseren Anzahl von Experimenten. Praktisch kann jedenfalls gesagt werden, das die beiden Alkaloide in ihrer Wirkung qualitativ und quantitativ identisch sind. Diese Identitat schliest aber eine chemische Differenz nicht aus, wenn es auch unwahrscheinlich ist, das sie sehr erheblich ist. Die Isolierung des Ergotamins fuhrt also nicht zu einer Umstellung der Pharmakologie des Mutterkorns, aber sie weist erneut auf die Bedeutung der spezifischen Alkaloide der Droge hin, die von deren zufalligen und unspezifischen Bestandteilen scharf unterschieden werden mussen. Jedenfalls steht und fallt der therapeutische Wert des Mutterkorns mit dem der beiden Alkaloide Ergotoxin und Ergotamin. Welches von diesen beiden man therapeutisch anwendet, wird allein von pharmazeutisch-technischen Bedingungen (Reinheitsgrad, Dosierbarkeit usw.) abhangen. Fur die Mutterkornextrakte wird es darauf ankommen, das sie die Alkaloide quantitative enthalten.

Related Organizations
  • BIP!
    Impact byBIP!
    citations
    The total number of citations received by all articles of the researcher of interest.
    41
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
    OpenAIRE UsageCounts
    Usage byUsageCounts
    visibility views 18
    download downloads 71
  • 18
    views
    71
    downloads
    Powered byOpenAIRE UsageCounts
Powered by OpenAIRE graph
Found an issue? Give us feedback
visibility
download
citations
The total number of citations received by all articles of the researcher of interest.
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
downloads
OpenAIRE UsageCountsDownloads provided by UsageCounts
41
Average
Top 1%
Average
18
71
Green
hybrid