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Abstract Ugi four‐center three‐component reaction (U‐4 C‐3CR) as actually an important development of the well‐known Ugi four‐component reaction (U‐4CR). In U‐4 C‐3CR, one of the components is bifunctional, reducing the components of U‐4CR to three components. This review aims to provide the application of U‐4 C‐3CR in the synthesis of different N ‐heterocyclic compounds with four‐, five‐, six‐, and seven‐membered rings as well as fused heterocycles.
Intramolecular Ugi reaction, Ugi four-center three-component reaction, Multicomponent reaction, Isocyanides, U-4 C-3CR
Intramolecular Ugi reaction, Ugi four-center three-component reaction, Multicomponent reaction, Isocyanides, U-4 C-3CR
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