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Advanced Intelligent Systems
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Advanced Intelligent Systems
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Advanced Intelligent Systems
Article . 2022 . Peer-reviewed
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Magnetically Guided Laser Surgery for the Treatment of Twin‐to‐Twin Transfusion Syndrome

Authors: Jonas Lussi; Simone Gervasoni; Michelle Mattille; Roland Dreyfus; Quentin Boehler; Michael Reinehr; Nicole Ochsenbein; +2 Authors
APC: 2,243 EUR

Magnetically Guided Laser Surgery for the Treatment of Twin‐to‐Twin Transfusion Syndrome

Abstract

Twin‐to‐twin transfusion syndrome (TTTS) is a severe disorder that often leads to the death of monochorionic twin fetuses, if left untreated. Current prenatal interventions to treat the condition involve the use of rigid fetoscopes for targeted laser coagulation of the vascular anastomoses. These tools are limited in their area of operation, making treatment challenging, especially in cases with anterior placentation. Herein, a robotic platform to perform this task using remote magnetic navigation is proposed. In contrast to rigid tools, the presented custom magnetic fetoscope is highly flexible, dexterous, and has considerable advantages, including safety and precision. A visual servoing algorithm that allows the surgeon to navigate in the uterus with submillimeter precision is introduced. The system has been validated on ex vivo human placentas in a setting that mimics the real intraoperative conditions.

Country
Switzerland
Keywords

Computer engineering. Computer hardware, fetal surgery, Control engineering systems. Automatic machinery (General), laser surgery, magnetic navigation systems, 610 Medicine & health, medical robotics, TK7885-7895, fetal surgery, laser surgery, magnetic navigation systems, medical robotics, twin-to-twin transfusion syndrome, 10049 Institute of Pathology and Molecular Pathology, TJ212-225, fetal surgery; laser surgery; magnetic navigation systems; medical robotics; twin-to-twin transfusion syndrome, General Earth and Planetary Sciences, General Environmental Science, twin-to-twin transfusion syndrome

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    16
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
16
Top 10%
Average
Top 10%
Green
gold