Gonorrhea is an acute, specific, infectious, systemic disease, with a local manifestation and systemic reaction. I am well aware that this statement is in variance with the almost universal statement of authors, but not so completely so with the clinician and more especially with the patient or victim. The victim of this disease, if allowed to tell his story, will give a history in the mild cases, which are but slightly infectious, of an aching in the limbs and back, just at the time of agglutination of the meatus, which, by the way, is a sign that precedes by some twenty-four hours the tingling or itching in the end of the penis, or the pearly drop so often spoken of. This acute symptom or aching will subside, usually, with the appearance of the discharge, when the local symptom (discharge) becomes the marked one, in fact the only manifest symptom. This