Reduced creatinine clearance is a significant indicator of kidney function decline. In this research activity, we aim to investigate the impact of reduced creatinine clearance on early health outcomes in patients with chronic kidney disease. The study will explore the relationship between creatinine clearance and various health parameters, including blood pressure, electrolyte levels, and cardiovascular risk factors. By understanding the effects of reduced creatinine clearance, we can develop targeted interventions to improve patient outcomes and slow disease progression.