Pyroptosis is a recently identified mechanism of programmed cell death related to Caspase-1 that triggers a series of inflammatory reactions by releasing severe inflammatory factors. This process is mediated by gasdermin D, which forms pores in the cell membrane, leading to cell lysis and the release of pro-inflammatory molecules. The role of pyroptosis in various diseases, including cancer, infection, and inflammatory disorders, has been extensively studied. However, the underlying mechanisms of pyroptosis and its regulation remain poorly understood. Further research is needed to elucidate the complex interactions between pyroptosis and other cellular processes, such as apoptosis and necroptosis.