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In vitro Susceptibility of Leishmania donovani to Miltefosine

appsOther research productkeyboard_double_arrow_right Research Activity 17 Aug 2010

In vitro Susceptibility of Leishmania donovani to Miltefosine

Abstract

Promastigote miltefosine (MIL) susceptibility was performed on Leishmania donovani isolates from Indian patients with visceral leishmaniasis treated with MIL. Isolates were cultured in the presence of increasing concentrations of MIL and their growth was monitored. The results showed that the isolates were resistant to MIL, with a minimum inhibitory concentration (MIC) of 10 μM. The study highlights the need for alternative treatments for visceral leishmaniasis.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average