The initial stages of fullerene and endohedral metallofullerene (EMF) synthesis in carbon-helium plasma at 1500 K and 2500 K have been simulated with quantum chemical molecular dynamics (MD) based on the density functional theory (DFT) method. The results of the simulation show that the fullerene and EMF molecules are formed in the plasma through the interaction of carbon and helium atoms. The fullerene molecules are formed in the plasma at 1500 K, while the EMF molecules are formed at 2500 K. The simulation results also show that the EMF molecules are more stable than the fullerene molecules.