The interaction between environmental enrichment, age, and PPARα has been explored in various studies. Environmental enrichment has been shown to promote neurogenesis and improve cognitive function, particularly in older adults. PPARα, a nuclear receptor, plays a crucial role in regulating lipid metabolism and energy homeostasis. The combination of environmental enrichment and PPARα activation may have synergistic effects on neuroprotection and cognitive enhancement. Further research is needed to fully understand the mechanisms underlying this interaction and its potential therapeutic applications.