Effects of single or multiple doses of L-carnitine on liver energetic metabolism of rats forced to run.

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1988 English Journal:The Journal of sports medicine and physical fitness, volume 28 (issn: 0022-4707,

Authors: Bobyleva Guarriero V; IANNONE, Anna; BELLEI, Monica; Muscatello U.;

pmid: 3230912

handle: 11380/703875

Effects of single or multiple doses of L-carnitine on liver energetic metabolism of rats forced to run.

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Abstract

The effects of treatment with a single dose of L-carnitine and of daily injection of carnitine for one month on liver energetic metabolism in both sedentary and acutely exercised rats were compared. The results show that the treatment with a single dose of carnitine enhances the aerobic metabolism of liver mitochondria in both resting and in running rats. On the contrary, the daily injection of carnitine for one month does not cause any significant effect on the aerobic metabolism of liver. Treatment with single or multiple doses of carnitine does not modify the serum concentration of cholesterol and of triglycerides in comparison with respective controls.

Related Organizations

University of Modena and Reggio Emilia
Italy

Keywords

Male, Physical Exertion, Rats, Inbred Strains, Motor Activity, Lipids, Rats, Liver, Carnitine, Animals, Animals Carnitine/*administration & dosage Energy Metabolism Lipids/blood Liver/drug effects/*metabolism Male Motor Activity *Physical Exertion Rats Rats; Inbred Strains, Energy Metabolism

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