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Anti-DNA antibodies and circulating immune complexes (C1q-IgG) in recurrent aphtous stomatitis.

Authors: Rodríguez-Archilla, A; Urquía, M; Gómez-Moreno, G; Ceballos, A;

Anti-DNA antibodies and circulating immune complexes (C1q-IgG) in recurrent aphtous stomatitis.

Abstract

Cette étude a pour but de déterminer les anticorps anti-ADN et les complexes immuns circulants C1q-IgG dans le sérum de 50 patients qui présentaient des aphtes mineurs au moment de l’étude et chez 50 contrôles. Les résultats obtenus sont en rapport avec les paramètres cliniques et chronologiques de la maladie. Nous avons trouvé des niveaux plus élevés d’anticorps anti-ADN chez les patients avec des aphtes mineurs, en comparaison avec les contrôles. Il existait une corrélation entre ces niveaux d’anticorps anti-ADN et le temps écoulé depuis le dernier épisode de la maladie (p<0.001). Il n’existait cependant pas de différences significatives entre les concentrations anti-ADN ni en ce qui concerne le nombre de récidives ni le nombre de lésions durant l’épisode.

Anti-DNA antibodies and circulating immune complexes (C1q-IgG) in sera from 50 patients with minor aphtae at the moment of study and 50 healthy controls, were determined. The obtained results were correlated with chronological and clinical parameters of the disease. Our findings show a greater number of patients than controls with higher values of anti-DNA antibodies. The time from the last active stage of the disease conditioned the anti-DNA antibody levels (p< 0.001). However, no significant differences among the number of recurrences in a year or the number of lesions in a ulcerative stage and the anti-DNA antibody concentrations were observed.

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Keywords

Male, anticorps anti-DNA, anticorps anti-DNA; complexes immuns circulants C1q-IgG; stomatite aphteuse récidivante, complexes immuns circulants C1q-IgG, Time Factors, recurrent aphtous stomatitis, Complement C1q, Antigen-Antibody Complex, DNA, Antibodies, anti-DNA antibodies; circulating immune complexes C1q-IgG; recurrent aphtous stomatitis, Immunoglobulin M, circulating immune complexes C1q-IgG, Recurrence, anti-DNA antibodies, stomatite aphteuse récidivante, Humans, Female, Stomatitis, Aphthous

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green