
Biosynthesis of aureofungin by Streptoverticillium cinnamoneum var, terricola was found to be an oxygen dependent reaction. An accelerated rate of aureofungin production, along with a better yield coefficient were obtained under conditions of enhanced aeration during fermentation. A higher oxygen transfer rate was found to stimulate aureofungin A, and suppresses aureofungin B formation.
Oxygen, Antifungal Agents, Streptomycetaceae, Polyenes, Culture Media
Oxygen, Antifungal Agents, Streptomycetaceae, Polyenes, Culture Media
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