[Linkage of allergic rhinitis with HLA-DRB alleles polymorphism].
To investigate whether susceptibility or resistance to allergic rhinitis associated with HLA-DRB alleles.Using PCR-SSP (sequence-specific primer polymerase chain reaction), we tested the frequency distribution of HLA-DRB alleles in 41 patients with allergic rhinitis (AR) and 41 healthy controls from Beijing China.The frequence of HLA-DRB1 * 0301.2 and HLA-DRB4 * 0101 was lower in AR than in controls (2.44% vs 17.07%, P < 0.05; 29.27% vs 51.22%, P < 0.05).HLA-DRB1 * 0301.2 and HLA-DRB4 * 0101 alleles might confer protection against AR.
- Beijing Haidian Hospital China (People's Republic of)
Adult, Male, Polymorphism, Genetic, Rhinitis, Allergic, Perennial, Genetic Linkage, Humans, Female, HLA-DR Antigens, Alleles
Adult, Male, Polymorphism, Genetic, Rhinitis, Allergic, Perennial, Genetic Linkage, Humans, Female, HLA-DR Antigens, Alleles
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).3 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!