Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6.
Copyright policy Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6.
We report here the full length cDNA sequence and the deduced amino-acid sequence of MyD88, a novel myeloid differentiation primary response gene activated in M1D+ myeloid precursors, following induction of terminal differentiation and growth arrest by IL6. Detectable levels of MyD88 RNA were observed in myeloid precursor enriched murine bone-marrow, but not in several other non-myeloid murine tissues.
- University of Pennsylvania United States
Time Factors, Base Sequence, Interleukin-6, Molecular Sequence Data, Gene Expression, Proteins, Bone Marrow Cells, Cell Differentiation, DNA, Antigens, Differentiation, Mice, Bone Marrow, Myeloid Differentiation Factor 88, Animals, Amino Acid Sequence, Cloning, Molecular, Receptors, Immunologic, Cells, Cultured, Adaptor Proteins, Signal Transducing
Time Factors, Base Sequence, Interleukin-6, Molecular Sequence Data, Gene Expression, Proteins, Bone Marrow Cells, Cell Differentiation, DNA, Antigens, Differentiation, Mice, Bone Marrow, Myeloid Differentiation Factor 88, Animals, Amino Acid Sequence, Cloning, Molecular, Receptors, Immunologic, Cells, Cultured, Adaptor Proteins, Signal Transducing
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