[The influence of electrical stimulation of the paleocerebellar cortex upon spike-wave activity induced at the early stage of corazol-induced kindling in rats].
Copyright policy )[The influence of electrical stimulation of the paleocerebellar cortex upon spike-wave activity induced at the early stage of corazol-induced kindling in rats].
Chronic Wistar rats experiments have shown that repeated administrations of corazol in subthreshold dosages (30.0 mg/kg, i.p.) were followed by spike-wave (SW) bursts of discharges. Duration of such bursts as well as common period of their registration were longer in the course of epileptogen administration. High-frequency (100 Hz0 electric stimulation of the paleocerebellar cortex decreased duration of SW-complexes and period of their registration while low-frequency (10 Hz) electric stimulation resulted in a short-term effect of reduction of duration of SW bursts.
Cerebral Cortex, Male, Kindling, Neurologic, Action Potentials, Animals, Pentylenetetrazole, Convulsants, Rats, Wistar, Electric Stimulation, Rats
Cerebral Cortex, Male, Kindling, Neurologic, Action Potentials, Animals, Pentylenetetrazole, Convulsants, Rats, Wistar, Electric Stimulation, Rats
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