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[Histophysiologic characteristics of the subcommissural organ during isolated suppression of the functional activity of the zona glomerulosa of the adrenal gland].

Authors: E S, Gul'iants; L P, Siziakina;

[Histophysiologic characteristics of the subcommissural organ during isolated suppression of the functional activity of the zona glomerulosa of the adrenal gland].

Abstract

The effect of prolonged administration of heparin on the histophysiological characteristics of the subcomissural organ (SCO) of the brain and adrenal glomerular zone (AGZ) was studied in 30 male rats. It was established that heparin inhibits the functional activity of AGZ adrenocorticocytes. This is associated with the lowered content of 3-beta-ol-steroid dehydrogenase, RNA, total protein, and a decrease in the zone width (by 50%). Ependimocytes of brain SCO show an abruptly reduced activity of glutamate dehydrogenase, NAD-dependent alpha-glycerophosphate dehydrogenase, lactate dehydrogenase acid phosphatase, which is evidence of their secretory function inhibition. The changes indicate the presence of the functional relationship between the ependimocytes of brain SCO and AGZ adrenocorticocytes as well as to the participation of brain SCO in AGZ function control.

Keywords

Male, Brain Mapping, 3-Hydroxysteroid Dehydrogenases, L-Lactate Dehydrogenase, Heparin, Histocytochemistry, Glycerolphosphate Dehydrogenase, Neurosecretory Systems, Rats, Succinate Dehydrogenase, Glutamate Dehydrogenase, Adrenal Cortex, Animals, Subcommissural Organ, Dihydrolipoamide Dehydrogenase

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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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