
Nanovesículas o nanoestructuras que semejan pequeñas bacterias de menos de 0,5 my m de diámetro han sido encontradas como contaminantes de sueros comerciales provenientes de fetos bovinos y fueron responsables de efectos citotóxicos en monocapas celulares cultivadas in vitro. Posteriormente el agente fue cultivado y clasificado como Nanobacterium sanguineum, el cual se ha relacionado con la formación de cálculos renales y más recientemente con otras patologías asociadas a calcificación de tejidos. Por otra parte, otros científicos no aceptan la existencia de tal bacteria. Se requiere más investigación para determinar si esas nanoestructuras son realmente bacterias Nanovesicles or nanostructures that resemble tiny bacteria of less than 0.5 mu m in diameter were finded as contaminants in commercial fetal bovine serum, and were responsible for the cytotoxicity on cell monolayer cultured in vitro. Then, the agent was isolated and classified as Nanobacterium sanguineum, it was associated with kidney stone formation and more recently with other pathologies producing calcification. In the other hand, none researchers do not accepted the existence of these bacteria. More studies must be done to determine whether the nanostructures observed are bacteria
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