The genome of the model beetle and pest Tribolium castaneum
Copyright policy )The genome of the model beetle and pest Tribolium castaneum
Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural products. We describe its genome sequence here. This omnivorous beetle has evolved the ability to interact with a diverse chemical environment, as shown by large expansions in odorant and gustatory receptors, as well as P450 and other detoxification enzymes. Development in Tribolium is more representative of other insects than is Drosophila, a fact reflected in gene content and function. For example, Tribolium has retained more ancestral genes involved in cell-cell communication than Drosophila, some being expressed in the growth zone crucial for axial elongation in short-germ development. Systemic RNA interference in T. castaneum functions differently from that in Caenorhabditis elegans, but nevertheless offers similar power for the elucidation of gene function and identification of targets for selective insect control.
- University of Mary United States
- Oklahoma State University System United States
- Imperial College London United Kingdom
- EUROPEAN MOLECULAR BIOLOGY LABORATORY Germany
- Nagoya University Japan
[SDE] Environmental Sciences, Repetitive Sequences, Nucleic Acid/genetics, Insecticides, Bombyx-mori, Proteome, Cytochrome P-450 Enzyme System/genetics, Genome, Insect, Diseases and Exotic Species in Farmland, Genes, Insect, Receptors, Odorant, 060407 Genome Structure and Regulation, Receptors, G-Protein-Coupled, G-Protein-Coupled Receptors, Genome, Insect/ genetics, Segmentation, Oogenesis, Cytochrome P-450 Enzyme System, Odorant Receptors, honey bee, species richness, Insect Genome, Phylogeny, Red Flour Beetle, Tribolium, Base Composition, Neurotransmitter Agents, Messenger RNA, beetle, Neurotransmitter Agents/genetics, Receptors, Odorant/genetics, article, cell communication, Vision, Ocular/genetics, Telomere, Insecticides/pharmacology, DNA Transposable Elements/genetics, Proteome/genetics, Genes, Insect/ genetics, Oogenesis/genetics, Taste, 960413 Control of Plant Pests, RNA Interference, ddc:570, Growth and Development, 570, identification method, 572, CEMAGREF, Nucleic Acid Repetitive Sequences, cytochrome P450, Taste/genetics, neurohormone, Arable Cropland and Permanent Cropland Environments, G protein coupled receptor, 570 Life Sciences, Drosophila-melanogaster, pest species, 610 Medical Sciences, Medicine, C1, Keywords: cysteine, 616, Short-Germ Insect, Insect Genes, Ocular Vision, Animals, Humans, Tribolium/classification/embryology/ genetics/physiology, detoxification, Caenorhabditis elegans, genome, Growth and Development/genetics, Telomere/genetics, Body Patterning, Repetitive Sequences, Nucleic Acid, Apis-mellifera, Protein, BELY, ECO, chemical environmen, Body Patterning/genetics, fly, Cardiovascular and Metabolic Diseases, Gene Superfamily, DNA Transposable Elements, Receptors, G-Protein-Coupled/genetics, pest control, ddc: ddc:616
[SDE] Environmental Sciences, Repetitive Sequences, Nucleic Acid/genetics, Insecticides, Bombyx-mori, Proteome, Cytochrome P-450 Enzyme System/genetics, Genome, Insect, Diseases and Exotic Species in Farmland, Genes, Insect, Receptors, Odorant, 060407 Genome Structure and Regulation, Receptors, G-Protein-Coupled, G-Protein-Coupled Receptors, Genome, Insect/ genetics, Segmentation, Oogenesis, Cytochrome P-450 Enzyme System, Odorant Receptors, honey bee, species richness, Insect Genome, Phylogeny, Red Flour Beetle, Tribolium, Base Composition, Neurotransmitter Agents, Messenger RNA, beetle, Neurotransmitter Agents/genetics, Receptors, Odorant/genetics, article, cell communication, Vision, Ocular/genetics, Telomere, Insecticides/pharmacology, DNA Transposable Elements/genetics, Proteome/genetics, Genes, Insect/ genetics, Oogenesis/genetics, Taste, 960413 Control of Plant Pests, RNA Interference, ddc:570, Growth and Development, 570, identification method, 572, CEMAGREF, Nucleic Acid Repetitive Sequences, cytochrome P450, Taste/genetics, neurohormone, Arable Cropland and Permanent Cropland Environments, G protein coupled receptor, 570 Life Sciences, Drosophila-melanogaster, pest species, 610 Medical Sciences, Medicine, C1, Keywords: cysteine, 616, Short-Germ Insect, Insect Genes, Ocular Vision, Animals, Humans, Tribolium/classification/embryology/ genetics/physiology, detoxification, Caenorhabditis elegans, genome, Growth and Development/genetics, Telomere/genetics, Body Patterning, Repetitive Sequences, Nucleic Acid, Apis-mellifera, Protein, BELY, ECO, chemical environmen, Body Patterning/genetics, fly, Cardiovascular and Metabolic Diseases, Gene Superfamily, DNA Transposable Elements, Receptors, G-Protein-Coupled/genetics, pest control, ddc: ddc:616
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