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pmid: 23215727
Investigation of HLA-B*35 subtypes and haplotypes among Croatians.4000 randomly selected unrelated donors from Croatian Bone Marrow Donor Registry were typed for HLA-A, -B and -DRB1 by PCR-LabType®SSO method.Four different B*35 alleles (*35:01, *35:02, *35:03, *35:08) were found. Three of them were with similar frequencies as in other European Caucasians, while HLA-B*35:03 was two times more frequent in our population. Predicted haplotypes were also in accordance with present data from other populations.This study should be of benefit in the unrelated haematopoietic stem cell transplantation (HSCT) program. It should facilitate the recipient-donor matching and the selection of a suitable population for further searches.
HLA-B*35, HLA-B*35; Croatian population; haplotypes, haplotypes, Polymorphism, Genetic, Croatia, Histocompatibility Testing, Hematopoietic Stem Cell Transplantation, Linkage Disequilibrium, White People, Croatian population, Gene Frequency, Haplotypes, Histocompatibility, Humans, Registries, HLA-B35 Antigen, Unrelated Donors, Bone Marrow Transplantation
HLA-B*35, HLA-B*35; Croatian population; haplotypes, haplotypes, Polymorphism, Genetic, Croatia, Histocompatibility Testing, Hematopoietic Stem Cell Transplantation, Linkage Disequilibrium, White People, Croatian population, Gene Frequency, Haplotypes, Histocompatibility, Humans, Registries, HLA-B35 Antigen, Unrelated Donors, Bone Marrow Transplantation
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